Cargando…

The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells

The human protein ASPG is an enzyme with a putative antitumor activity. We generated in bacteria and then purified a recombinant GST-ASPG protein that we used to characterize the biochemical and cytotoxic properties of the human ASPG. We demonstrated that ASPG possesses asparaginase and PAF acetylhy...

Descripción completa

Detalles Bibliográficos
Autores principales: Belviso, Stefania, Iuliano, Rodolfo, Amato, Rosario, Perrotti, Nicola, Menniti, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443537/
https://www.ncbi.nlm.nih.gov/pubmed/28542249
http://dx.doi.org/10.1371/journal.pone.0178174