Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants

Obesity is a multifactorial disorder with high heritability (50–75%), which is probably higher in early-onset and severe cases. Although rare monogenic forms and several genes and regions of susceptibility, including copy number variants (CNVs), have been described, the genetic causes underlying the...

Descripción completa

Detalles Bibliográficos
Autores principales: Serra-Juhé, Clara, Martos-Moreno, Gabriel Á., Bou de Pieri, Francesc, Flores, Raquel, González, Juan R., Rodríguez-Santiago, Benjamín, Argente, Jesús, Pérez-Jurado, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443539/
https://www.ncbi.nlm.nih.gov/pubmed/28489853
http://dx.doi.org/10.1371/journal.pgen.1006657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443539/
https://www.ncbi.nlm.nih.gov/pubmed/28489853
http://dx.doi.org/10.1371/journal.pgen.1006657

Ejemplares similares