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Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants
Obesity is a multifactorial disorder with high heritability (50–75%), which is probably higher in early-onset and severe cases. Although rare monogenic forms and several genes and regions of susceptibility, including copy number variants (CNVs), have been described, the genetic causes underlying the...
Autores principales: | Serra-Juhé, Clara, Martos-Moreno, Gabriel Á., Bou de Pieri, Francesc, Flores, Raquel, González, Juan R., Rodríguez-Santiago, Benjamín, Argente, Jesús, Pérez-Jurado, Luis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443539/ https://www.ncbi.nlm.nih.gov/pubmed/28489853 http://dx.doi.org/10.1371/journal.pgen.1006657 |
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