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Gene signature associated with benign neurofibroma transformation to malignant peripheral nerve sheath tumors

Benign neurofibromas, the main phenotypic manifestations of the rare neurological disorder neurofibromatosis type 1, degenerate to malignant tumors associated to poor prognosis in about 10% of patients. Despite efforts in the field of (epi)genomics, the lack of prognostic biomarkers with which to pr...

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Detalles Bibliográficos
Autores principales: Martínez, Marta, Sorzano, Carlos O. S., Pascual-Montano, Alberto, Carazo, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443557/
https://www.ncbi.nlm.nih.gov/pubmed/28542306
http://dx.doi.org/10.1371/journal.pone.0178316