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Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease

Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We postulated that exaggerated sympathetically mediated vasoconstriction, endothelial dysfunction and the synergistic interaction between these...

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Detalles Bibliográficos
Autores principales: Chalacheva, Patjanaporn, Khaleel, Maha, Sunwoo, John, Shah, Payal, Detterich, Jon A., Kato, Roberta M., Thuptimdang, Wanwara, Meiselman, Herbert J., Sposto, Richard, Tsao, Jennie, Wood, John C., Zeltzer, Lonnie, Coates, Thomas D., Khoo, Michael C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443571/
https://www.ncbi.nlm.nih.gov/pubmed/28542469
http://dx.doi.org/10.1371/journal.pone.0178353