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Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease
Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We postulated that exaggerated sympathetically mediated vasoconstriction, endothelial dysfunction and the synergistic interaction between these...
Autores principales: | Chalacheva, Patjanaporn, Khaleel, Maha, Sunwoo, John, Shah, Payal, Detterich, Jon A., Kato, Roberta M., Thuptimdang, Wanwara, Meiselman, Herbert J., Sposto, Richard, Tsao, Jennie, Wood, John C., Zeltzer, Lonnie, Coates, Thomas D., Khoo, Michael C. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443571/ https://www.ncbi.nlm.nih.gov/pubmed/28542469 http://dx.doi.org/10.1371/journal.pone.0178353 |
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