Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature

Sequencing of whole tumor genomes holds the promise of revealing functional somatic regulatory mutations, such as those described in the TERT promoter. Recurrent promoter mutations have been identified in many additional genes and appear to be particularly common in melanoma, but convincing function...

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Detalles Bibliográficos
Autores principales: Fredriksson, Nils Johan, Elliott, Kerryn, Filges, Stefan, Van den Eynden, Jimmy, Ståhlberg, Anders, Larsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443578/
https://www.ncbi.nlm.nih.gov/pubmed/28489852
http://dx.doi.org/10.1371/journal.pgen.1006773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443578/
https://www.ncbi.nlm.nih.gov/pubmed/28489852
http://dx.doi.org/10.1371/journal.pgen.1006773

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