The Absence of Interferon-β Promotor Stimulator-1 (IPS-1) Predisposes to Bronchiolitis and Asthma-like Pathology in Response to Pneumoviral Infection in Mice

Respiratory syncytial virus (RSV)-bronchiolitis is a major cause of infant morbidity and mortality and a risk factor for subsequent asthma. We showed previously that toll-like receptor (TLR)7 in plasmacytoid dendritic cells (pDCs) is critical for protection against bronchiolitis and asthma in mice i...

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Detalles Bibliográficos
Autores principales: Simpson, Jennifer, Lynch, Jason P., Loh, Zhixuan, Zhang, Vivian, Werder, Rhiannon B., Spann, Kirsten, Phipps, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443759/
https://www.ncbi.nlm.nih.gov/pubmed/28539639
http://dx.doi.org/10.1038/s41598-017-02564-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443759/
https://www.ncbi.nlm.nih.gov/pubmed/28539639
http://dx.doi.org/10.1038/s41598-017-02564-9

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