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Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4

Angiopoietins are a family of growth factors that are ligands for the tyrosine kinase receptor, Tie2. Angiopoietin 1 (Ang-1) is agonistic for Tie2, plays a key role in blood vessel maturation and stability and has been shown to possess anti-inflammatory properties. However, Tie2 expression has been...

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Detalles Bibliográficos
Autores principales: Burnett, Amanda, Gomez, Ingrid, De Leon, David Davila, Ariaans, Mark, Progias, Pavlos, Kammerer, Richard A., Velasco, Guillermo, Marron, Marie, Hellewell, Paul, Ridger, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443761/
https://www.ncbi.nlm.nih.gov/pubmed/28539655
http://dx.doi.org/10.1038/s41598-017-02216-y