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Optogenetic excitation of cholinergic inputs to hippocampus primes future contextual fear associations

Learning about context is essential for appropriate behavioral strategies, but important contingencies may not arise during initial learning. A variant of contextual fear conditioning, context pre-exposure facilitation, allows us to directly test the relationship between novelty-induced acetylcholin...

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Detalles Bibliográficos
Autores principales: Hersman, Sarah, Cushman, Jesse, Lemelson, Noah, Wassum, Kate, Lotfipour, Shahrdad, Fanselow, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443779/
https://www.ncbi.nlm.nih.gov/pubmed/28539613
http://dx.doi.org/10.1038/s41598-017-02542-1