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Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome

Ribosomal protein (RP) L23 is a negative regulator of cellular apoptosis, and RPL23 overexpression is associated with abnormal apoptotic resistance in CD34+ cells derived from patients with higher-risk myelodysplastic syndrome (MDS). However, the mechanism underlying RPL23-induced apoptotic resistan...

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Detalles Bibliográficos
Autores principales: Qi, Yuekun, Li, Xiao, Chang, Chunkang, Xu, Feng, He, Qi, Zhao, Youshan, Wu, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443795/
https://www.ncbi.nlm.nih.gov/pubmed/28539603
http://dx.doi.org/10.1038/s41598-017-02403-x