Cargando…

Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome

Ribosomal protein (RP) L23 is a negative regulator of cellular apoptosis, and RPL23 overexpression is associated with abnormal apoptotic resistance in CD34+ cells derived from patients with higher-risk myelodysplastic syndrome (MDS). However, the mechanism underlying RPL23-induced apoptotic resistan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Yuekun, Li, Xiao, Chang, Chunkang, Xu, Feng, He, Qi, Zhao, Youshan, Wu, Lingyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443795/ https://www.ncbi.nlm.nih.gov/pubmed/28539603 http://dx.doi.org/10.1038/s41598-017-02403-x

Ejemplares similares

Arabidopsis paralogous genes RPL23aA and RPL23aB encode functionally equivalent proteins
por: Xiong, Wei, et al.
Publicado: (2020)

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
por: Gebhardt, Anneli, et al.
Publicado: (2006)

High expression of APAF-1 elevates erythroid apoptosis in iron overload myelodysplastic syndrome
por: Gu, Shucheng, et al.
Publicado: (2013)

cDNA Cloning, Overexpression, Purification and Pharmacologic Evaluation for Anticancer Activity of Ribosomal Protein L23A Gene (RPL23A) from the Giant Panda
por: Sun, Bing, et al.
Publicado: (2012)

Regulation of Hedgehog Signaling by Myc-Interacting Zinc Finger Protein 1, Miz1
por: Lu, Jiuyi, et al.
Publicado: (2013)

Tipping the MYC–MIZ1 balance: targeting the HUWE1 ubiquitin ligase selectively blocks MYC-activated genes
por: Schaub, Franz X, et al.
Publicado: (2014)

Decreased FOXO1 Expression Is Correlated with Poor Prognosis in Myelodysplastic Syndromes
por: Zhang, Zheng, et al.
Publicado: (2022)

Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism
por: Lezzerini, Marco, et al.
Publicado: (2020)

RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis
por: Alkhatabi, Heba A., et al.
Publicado: (2016)

Evidence of Horizontal Gene Transfer of 50S Ribosomal Genes rplB, rplD, and rplY in Neisseria gonorrhoeae
por: Manoharan-Basil, Sheeba Santhini, et al.
Publicado: (2021)

Myc interacts with Max and Miz1 to repress C/EBPδ promoter activity and gene expression
por: Si, Junling, et al.
Publicado: (2010)

MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation
por: Shostak, Anton, et al.
Publicado: (2016)

The rpl23 gene and pseudogene are hotspots of illegitimate recombination in barley chloroplast mutator seedlings
por: Lencina, F., et al.
Publicado: (2019)

Iron overload promotes mitochondrial fragmentation in mesenchymal stromal cells from myelodysplastic syndrome patients through activation of the AMPK/MFF/Drp1 pathway
por: Zheng, Qingqing, et al.
Publicado: (2018)

PB2013: THE FREQUENCY, EVOLUTION AND SIGNIFICANCE OF GENE MUTATION IN MYELODYSPLASTIC SYNDROMES WITH NORMAL KARYOTYPE
por: Xu, Feng, et al.
Publicado: (2023)

The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog, Rpl22l1
por: O'Leary, Monique N., et al.
Publicado: (2013)

Eukaryotic rpL10 drives ribosomal rotation
por: Sulima, Sergey O., et al.
Publicado: (2014)

Role of MIZ-1 in AMELX gene expression
por: Noh, Hee-Jin, et al.
Publicado: (2016)

HERC3 directly targets RPL23A for ubiquitination degradation and further regulates Colorectal Cancer proliferation and the cell cycle
por: Zhang, Zhiyuan, et al.
Publicado: (2022)

Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells
por: Varlakhanova, Natalia, et al.
Publicado: (2011)

Myc-Interacting Zinc Finger Protein 1 (Miz-1) Is Essential to Maintain Homeostasis and Immunocompetence of the B Cell Lineage
por: Piskor, Eva-Maria, et al.
Publicado: (2022)

Cellular senescence induced by S100A9 in mesenchymal stromal cells through NLRP3 inflammasome activation
por: Shi, Lei, et al.
Publicado: (2019)

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
por: Zou, Qianxing, et al.
Publicado: (2021)

Functional analysis of Saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis
por: Rosado, Iván V., et al.
Publicado: (2007)

The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis
por: Herkert, Barbara, et al.
Publicado: (2010)

Arf and Miz1 cause cells to lose their grip
por: Short, Ben
Publicado: (2010)

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart
por: Milenkovic, Ivan, et al.
Publicado: (2023)

USP19 and RPL23 as Candidate Prognostic Markers for Advanced-Stage High-Grade Serous Ovarian Carcinoma
por: Kang, Haeyoun, et al.
Publicado: (2021)

Plant Ribosomal Proteins, RPL12 and RPL19, Play a Role in Nonhost Disease Resistance against Bacterial Pathogens
por: Nagaraj, Satish, et al.
Publicado: (2016)

RPL-4 and RPL-9 –Mediated Ribosome Purifications Facilitate the Efficient Analysis of Gene Expression in Caenorhabditis elegans Germ Cells
por: Nousch, Marco
Publicado: (2020)

Schwann cell Miz without POZ: degeneration meets regeneration
por: Fuhrmann, David, et al.
Publicado: (2015)

Bone Marrow Fibrosis at Diagnosis and during the Course of Disease Is Associated with TP53 Mutations and Adverse Prognosis in Primary Myelodysplastic Syndrome
por: Zhao, Youshan, et al.
Publicado: (2022)

Paralog-Specific Functions of RPL7A and RPL7B Mediated by Ribosomal Protein or snoRNA Dosage in Saccharomyces cerevisiae
por: Palumbo, Ryan J., et al.
Publicado: (2016)

Expression Profiling of Ribosomal Protein Gene Family in Dehydration Stress Responses and Characterization of Transgenic Rice Plants Overexpressing RPL23A for Water-Use Efficiency and Tolerance to Drought and Salt Stresses
por: Moin, Mazahar, et al.
Publicado: (2017)

Effector protein Hcp2a of avian pathogenic Escherichia coli interacts with the endoplasmatic reticulum associated RPL23 protein of chicken DF-1 fibroblasts
por: Chen, Zhe, et al.
Publicado: (2023)

Methylation of yeast ribosomal protein Rpl3 promotes translational elongation fidelity
por: Al-Hadid, Qais, et al.
Publicado: (2016)

Dosage Sensitivity of RPL9 and Concerted Evolution of Ribosomal Protein Genes in Plants
por: Devis, Deborah, et al.
Publicado: (2015)

Regulation of CDKN2B expression by interaction of Arnt with Miz-1 - a basis for functional integration between the HIF and Myc gene regulatory pathways
por: Aesoy, Reidun, et al.
Publicado: (2014)

Nac1 interacts with the POZ-domain transcription factor, Miz1
por: Stead, Mark A., et al.
Publicado: (2014)

Commentary on Facial Rejuvenation with Fine Barbed Threads: The Simple MIZ-Lift
por: Wu, Woffles T. L.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_hhqdhps2uab86jsksp6p99hkp0