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Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans

The programmed induction of meiotic DNA double-strand breaks (DSBs) by the evolutionarily conserved SPO-11 protein, which is structurally related to archaeal Topo VIA topoisomerases, triggers meiotic recombination. Identification of several meiosis-specific factors that are required for SPO-11-media...

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Detalles Bibliográficos
Autores principales: Yeh, Hsin-Yi, Lin, Sheng-Wei, Wu, Yi-Chun, Chan, Nei-Li, Chi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443798/
https://www.ncbi.nlm.nih.gov/pubmed/28539630
http://dx.doi.org/10.1038/s41598-017-02641-z