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Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice

Runx2 may play an important role in development of osteoarthritis (OA). However, the specific role of Runx2 in articular chondrocyte function and in OA development in adult mice has not been fully defined. In this study, we performed the destabilization of the medial meniscus (DMM) surgery at 12-wee...

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Detalles Bibliográficos
Autores principales: Liao, Lifan, Zhang, Shanxing, Gu, Jianhong, Takarada, Takeshi, Yoneda, Yukio, Huang, Jian, Zhao, Lan, Oh, Chun-do, Li, Jun, Wang, Baoli, Wang, Meiqing, Chen, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443810/
https://www.ncbi.nlm.nih.gov/pubmed/28539595
http://dx.doi.org/10.1038/s41598-017-02490-w