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Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations

The bright fluorescent cytosine analogue tC(O) stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA. We here report on the first synthesis and RNA-incorporat...

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Detalles Bibliográficos
Autores principales: Füchtbauer, Anders Foller, Preus, Søren, Börjesson, Karl, McPhee, Scott A., Lilley, David M. J., Wilhelmsson, L. Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443824/
https://www.ncbi.nlm.nih.gov/pubmed/28539582
http://dx.doi.org/10.1038/s41598-017-02453-1