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Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations
The bright fluorescent cytosine analogue tC(O) stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA. We here report on the first synthesis and RNA-incorporat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443824/ https://www.ncbi.nlm.nih.gov/pubmed/28539582 http://dx.doi.org/10.1038/s41598-017-02453-1 |