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ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth

Cry1A insecticidal toxins bind sequentially to different larval gut proteins facilitating oligomerization, membrane insertion and pore formation. Cry1Ac interaction with cadherin triggers oligomerization. However, a mutation in an ABC transporter gene (ABCC2) is linked to Cry1Ac resistance in Plutel...

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Detalles Bibliográficos
Autores principales: Ocelotl, Josue, Sánchez, Jorge, Gómez, Isabel, Tabashnik, Bruce E., Bravo, Alejandra, Soberón, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443830/
https://www.ncbi.nlm.nih.gov/pubmed/28539590
http://dx.doi.org/10.1038/s41598-017-02545-y