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Metalloproteinases ADAM10 and ADAM17 Mediate Migration and Differentiation in Glioblastoma Sphere-Forming Cells

Glioblastoma is the most common form of primary malignant brain tumour. These tumours are highly proliferative and infiltrative resulting in a median patient survival of only 14 months from diagnosis. The current treatment regimens are ineffective against the small population of cancer stem cells re...

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Detalles Bibliográficos
Autores principales: Siney, Elodie J., Holden, Alexander, Casselden, Elizabeth, Bulstrode, Harry, Thomas, Gareth J., Willaime-Morawek, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443867/
https://www.ncbi.nlm.nih.gov/pubmed/27541285
http://dx.doi.org/10.1007/s12035-016-0053-6