New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination

Conventional vaccines afford protection against infectious diseases by expanding existing pathogen-specific peripheral lymphocytes, both CD8 cytotoxic effector (CTL) and CD4 helper T cells. The latter induce B cell maturation and antibody production. As a consequence, lymphocytes within the memory p...

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Detalles Bibliográficos
Autores principales: Fridkis-Hareli, Masha, Reinherz, Ellis L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544398/
https://www.ncbi.nlm.nih.gov/pubmed/15588284
http://dx.doi.org/10.1186/1476-9433-3-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544398/
https://www.ncbi.nlm.nih.gov/pubmed/15588284
http://dx.doi.org/10.1186/1476-9433-3-2

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