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New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination
Conventional vaccines afford protection against infectious diseases by expanding existing pathogen-specific peripheral lymphocytes, both CD8 cytotoxic effector (CTL) and CD4 helper T cells. The latter induce B cell maturation and antibody production. As a consequence, lymphocytes within the memory p...
Autores principales: | Fridkis-Hareli, Masha, Reinherz, Ellis L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544398/ https://www.ncbi.nlm.nih.gov/pubmed/15588284 http://dx.doi.org/10.1186/1476-9433-3-2 |
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