Label-Free and Real-Time Detection of Protein Ubiquitination with a Biological Nanopore

[Image: see text] The covalent addition of ubiquitin to target proteins is a key post-translational modification that is linked to a myriad of biological processes. Here, we report a fast, single-molecule, and label-free method to probe the ubiquitination of proteins employing an engineered Cytolysi...

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Detalles Bibliográficos
Autores principales: Wloka, Carsten, Van Meervelt, Veerle, van Gelder, Dewi, Danda, Natasha, Jager, Nienke, Williams, Chris P., Maglia, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444049/
https://www.ncbi.nlm.nih.gov/pubmed/28353339
http://dx.doi.org/10.1021/acsnano.6b07760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444049/
https://www.ncbi.nlm.nih.gov/pubmed/28353339
http://dx.doi.org/10.1021/acsnano.6b07760

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