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Label-Free and Real-Time Detection of Protein Ubiquitination with a Biological Nanopore
[Image: see text] The covalent addition of ubiquitin to target proteins is a key post-translational modification that is linked to a myriad of biological processes. Here, we report a fast, single-molecule, and label-free method to probe the ubiquitination of proteins employing an engineered Cytolysi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444049/ https://www.ncbi.nlm.nih.gov/pubmed/28353339 http://dx.doi.org/10.1021/acsnano.6b07760 |