Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion

OBJECTIVES: Genome-wide association studies (GWAS) have identified >100 loci independently contributing to type 2 diabetes (T2D) risk. However, translational implications for precision medicine and for the development of novel treatments have been disappointing, due to poor knowledge of how these...

Descripción completa

Detalles Bibliográficos
Autores principales: Ndiaye, Fatou K., Ortalli, Ana, Canouil, Mickaël, Huyvaert, Marlène, Salazar-Cardozo, Clara, Lecoeur, Cécile, Verbanck, Marie, Pawlowski, Valérie, Boutry, Raphaël, Durand, Emmanuelle, Rabearivelo, Iandry, Sand, Olivier, Marselli, Lorella, Kerr-Conte, Julie, Chandra, Vikash, Scharfmann, Raphaël, Poulain-Godefroy, Odile, Marchetti, Piero, Pattou, François, Abderrahmani, Amar, Froguel, Philippe, Bonnefond, Amélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444093/
https://www.ncbi.nlm.nih.gov/pubmed/28580277
http://dx.doi.org/10.1016/j.molmet.2017.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444093/
https://www.ncbi.nlm.nih.gov/pubmed/28580277
http://dx.doi.org/10.1016/j.molmet.2017.03.011

Ejemplares similares