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Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemia

OBJECTIVE: The adipose-derived hormone leptin plays an important role in regulating body weight and glucose homeostasis. Leptin receptors are expressed in the central nervous system as well as peripheral tissues involved in regulating glucose homeostasis, including insulin-producing β cells of the p...

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Detalles Bibliográficos
Autores principales: D'souza, Anna M., Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444109/
https://www.ncbi.nlm.nih.gov/pubmed/28580288
http://dx.doi.org/10.1016/j.molmet.2017.04.003