Endocannabinoid-dependent disinhibition of orexinergic neurons: Electrophysiological evidence in leptin-knockout obese mice

OBJECTIVES: In the ob/ob mouse model of obesity, chronic absence of leptin causes a significant increase of orexin (OX) production by hypothalamic neurons and excessive food intake. The altered OX level is linked to a dramatic increase of the inhibitory innervation of OX producing neurons (OX neuron...

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Detalles Bibliográficos
Autores principales: Becker, Thorsten Michael, Favero, Morgana, Di Marzo, Vincenzo, Cristino, Luigia, Busetto, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444110/
https://www.ncbi.nlm.nih.gov/pubmed/28580289
http://dx.doi.org/10.1016/j.molmet.2017.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444110/
https://www.ncbi.nlm.nih.gov/pubmed/28580289
http://dx.doi.org/10.1016/j.molmet.2017.04.005

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