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Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure–Lowering Effects of Latanoprost

PURPOSE: To identify downstream signaling molecules through which intraocular pressure (IOP) is lowered following treatment with the prostaglandin analog latanoprost. METHODS: Total RNA and protein isolated from primary human Schlemm's canal cells (n = 3) treated with latanoprost (free acid; 10...

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Detalles Bibliográficos
Autores principales: Roddy, Gavin W., Viker, Kimberly B., Winkler, Nelson S., Bahler, Cindy K., Holman, Bradley H., Sheikh-Hamad, David, Roy Chowdhury, Uttio, Stamer, W. Daniel, Fautsch, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444548/
https://www.ncbi.nlm.nih.gov/pubmed/28538979
http://dx.doi.org/10.1167/iovs.16-21004