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An atypical role for the myeloid receptor Mincle in central nervous system injury

The C-type lectin Mincle is implicated in innate immune responses to sterile inflammation, but its contribution to associated pathologies is not well understood. Herein, we show that Mincle exacerbates neuronal loss following ischemic but not traumatic spinal cord injury. Loss of Mincle was benefici...

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Detalles Bibliográficos
Autores principales: Arumugam, Thiruma V, Manzanero, Silvia, Furtado, Milena, Biggins, Patrick J, Hsieh, Yu-Hsuan, Gelderblom, Mathias, MacDonald, Kelli PA, Salimova, Ekaterina, Li, Yu-I, Korn, Othmar, Dewar, Deborah, Macrae, I Mhairi, Ashman, Robert B, Tang, Sung-Chun, Rosenthal, Nadia A, Ruitenberg, Marc J, Magnus, Tim, Wells, Christine A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444551/
https://www.ncbi.nlm.nih.gov/pubmed/27492949
http://dx.doi.org/10.1177/0271678X16661201