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A Split Staphylococcus aureus Cas9 as a Compact Genome-Editing Tool in Plants
Split-protein methods—where a protein is split into two inactive fragments that must re-assemble to form an active protein—can be used to regulate the activity of a given protein and reduce the size of gene transcription units. Here, we show that a Staphylococcus aureus Cas9 (SaCas9) can be split, a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444561/ https://www.ncbi.nlm.nih.gov/pubmed/28371831 http://dx.doi.org/10.1093/pcp/pcx034 |