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UV-B induced fibrillization of crystallin protein mixtures

Environmental factors, mainly oxidative stress and exposure to sunlight, induce the oxidation, cross-linking, cleavage, and deamination of crystallin proteins, resulting in their aggregation and, ultimately, cataract formation. Various denaturants have been used to initiate the aggregation of crysta...

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Detalles Bibliográficos
Autores principales: Cetinel, Sibel, Semenchenko, Valentyna, Cho, Jae-Young, Sharaf, Mehdi Ghaffari, Damji, Karim F., Unsworth, Larry D., Montemagno, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444657/
https://www.ncbi.nlm.nih.gov/pubmed/28542382
http://dx.doi.org/10.1371/journal.pone.0177991