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UV-B induced fibrillization of crystallin protein mixtures
Environmental factors, mainly oxidative stress and exposure to sunlight, induce the oxidation, cross-linking, cleavage, and deamination of crystallin proteins, resulting in their aggregation and, ultimately, cataract formation. Various denaturants have been used to initiate the aggregation of crysta...
Autores principales: | Cetinel, Sibel, Semenchenko, Valentyna, Cho, Jae-Young, Sharaf, Mehdi Ghaffari, Damji, Karim F., Unsworth, Larry D., Montemagno, Carlo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444657/ https://www.ncbi.nlm.nih.gov/pubmed/28542382 http://dx.doi.org/10.1371/journal.pone.0177991 |
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