Thermodynamic framework to assess low abundance DNA mutation detection by hybridization

The knowledge of genomic DNA variations in patient samples has a high and increasing value for human diagnostics in its broadest sense. Although many methods and sensors to detect or quantify these variations are available or under development, the number of underlying physico-chemical detection pri...

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Detalles Bibliográficos
Autores principales: Willems, Hanny, Jacobs, An, Hadiwikarta, Wahyu Wijaya, Venken, Tom, Valkenborg, Dirk, Van Roy, Nadine, Vandesompele, Jo, Hooyberghs, Jef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444680/
https://www.ncbi.nlm.nih.gov/pubmed/28542229
http://dx.doi.org/10.1371/journal.pone.0177384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444680/
https://www.ncbi.nlm.nih.gov/pubmed/28542229
http://dx.doi.org/10.1371/journal.pone.0177384

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