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Thermodynamic framework to assess low abundance DNA mutation detection by hybridization
The knowledge of genomic DNA variations in patient samples has a high and increasing value for human diagnostics in its broadest sense. Although many methods and sensors to detect or quantify these variations are available or under development, the number of underlying physico-chemical detection pri...
Autores principales: | Willems, Hanny, Jacobs, An, Hadiwikarta, Wahyu Wijaya, Venken, Tom, Valkenborg, Dirk, Van Roy, Nadine, Vandesompele, Jo, Hooyberghs, Jef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444680/ https://www.ncbi.nlm.nih.gov/pubmed/28542229 http://dx.doi.org/10.1371/journal.pone.0177384 |
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