Chronic intratracheal application of the soluble guanylyl cyclase stimulator BAY 41-8543 ameliorates experimental pulmonary hypertension

Dysfunction of the NO/sGC/cGMP signaling pathway has been implicated in the pathogenesis of pulmonary hypertension (PH). Therefore, agents stimulating cGMP synthesis via sGC are important therapeutic options for treatment of PH patients. An unwanted effect of this novel class of drugs is their syste...

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Detalles Bibliográficos
Autores principales: Amirjanians, Matthieu, Egemnazarov, Bakytbek, Sydykov, Akylbek, Kojonazarov, Baktybek, Brandes, Ralf, Luitel, Himal, Pradhan, Kabita, Stasch, Johannes-Peter, Redlich, Gorden, Weissmann, Norbert, Grimminger, Friedrich, Seeger, Werner, Ghofrani, Hossein, Schermuly, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444690/
https://www.ncbi.nlm.nih.gov/pubmed/28410199
http://dx.doi.org/10.18632/oncotarget.16769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444690/
https://www.ncbi.nlm.nih.gov/pubmed/28410199
http://dx.doi.org/10.18632/oncotarget.16769

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