A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT

Targeted cancer therapy aims to disrupt aberrant cellular signalling pathways. Biomarkers are surrogates of pathway state, but there is limited success in translating candidate biomarkers to clinical practice due to the intrinsic complexity of pathway networks. Systems biology approaches afford bett...

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Detalles Bibliográficos
Autores principales: Bown, James L., Shovman, Mark, Robertson, Paul, Boiko, Andrei, Goltsov, Alexey, Mullen, Peter, Harrison, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444693/
https://www.ncbi.nlm.nih.gov/pubmed/27302920
http://dx.doi.org/10.18632/oncotarget.8747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444693/
https://www.ncbi.nlm.nih.gov/pubmed/27302920
http://dx.doi.org/10.18632/oncotarget.8747

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