Genetic profiling of a rare condition: co-occurrence of albinism and multiple primary melanoma in a caucasian family

Multiple primary melanoma (MPM) is a rare condition, whose genetic basis has not yet been clarified. Only 8-12% of MPM are due to germline mutations of CDKN2A. However, other genes (POT1, BRCA1/2, MC1R, MGMT) have been demonstrated to be involved in predisposition to this pathology. To our knowledge...

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Detalles Bibliográficos
Autores principales: De Summa, Simona, Guida, Michele, Tommasi, Stefania, Strippoli, Sabino, Pellegrini, Cristina, Concetta Fargnoli, Maria, Pilato, Brunella, Natalicchio, Iole, Guida, Gabriella, Pinto, Rosamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444700/
https://www.ncbi.nlm.nih.gov/pubmed/27776349
http://dx.doi.org/10.18632/oncotarget.12777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444700/
https://www.ncbi.nlm.nih.gov/pubmed/27776349
http://dx.doi.org/10.18632/oncotarget.12777

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