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Peroxynitrite dominates sodium nitroprusside-induced apoptosis in human hepatocellular carcinoma cells

This study aims to explore which radicals dominate sodium nitroprusside (SNP)-induced cytotoxicity in human hepatocellular carcinoma (HCC) cells (HepG2 and Hep3B). Exposure of SNP to cell medium produced abundant nitric oxide (NO), superoxide anion (O(2)(·−)), hydrogen peroxide (H(2)O(2)) and iron i...

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Detalles Bibliográficos
Autores principales: Quan, Ying-Yao, Liu, Yu-Hong, Lin, Chun-Mei, Wang, Xiao-Ping, Chen, Tong-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444707/
https://www.ncbi.nlm.nih.gov/pubmed/28415737
http://dx.doi.org/10.18632/oncotarget.16164