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Peroxynitrite dominates sodium nitroprusside-induced apoptosis in human hepatocellular carcinoma cells
This study aims to explore which radicals dominate sodium nitroprusside (SNP)-induced cytotoxicity in human hepatocellular carcinoma (HCC) cells (HepG2 and Hep3B). Exposure of SNP to cell medium produced abundant nitric oxide (NO), superoxide anion (O(2)(·−)), hydrogen peroxide (H(2)O(2)) and iron i...
Autores principales: | Quan, Ying-Yao, Liu, Yu-Hong, Lin, Chun-Mei, Wang, Xiao-Ping, Chen, Tong-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444707/ https://www.ncbi.nlm.nih.gov/pubmed/28415737 http://dx.doi.org/10.18632/oncotarget.16164 |
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