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Misregulation of DNA damage repair pathways in HPV-positive head and neck squamous cell carcinoma contributes to cellular radiosensitivity

Patients with human papillomavirus type 16 (HPV)-associated oropharyngeal squamous cell carcinomas (OPSCC) display increased sensitivity to radiotherapy and improved survival rates in comparison to HPV-negative forms of the disease. However the cellular mechanisms responsible for this characteristic...

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Detalles Bibliográficos
Autores principales: Nickson, Catherine M., Moori, Parisa, Carter, Rachel J., Rubbi, Carlos P., Parsons, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444717/
https://www.ncbi.nlm.nih.gov/pubmed/28415784
http://dx.doi.org/10.18632/oncotarget.16265