OSR1 is a novel epigenetic silenced tumor suppressor regulating invasion and proliferation in renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most malignant tumors in human. Here, we found that odd-skipped related transcription factor 1 (OSR1) was downregulated in 769-P and 786-O cells due to promoter CpG methylation. OSR1 expression could be restored by pharmacological demethylation treatment in s...

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Detalles Bibliográficos
Autores principales: Zhang, Yixiang, Yuan, Yeqing, Liang, Pei, Guo, Xiaojing, Ying, Ying, Shu, Xing-sheng, Gao, Michael, Cheng, Yingduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444721/
https://www.ncbi.nlm.nih.gov/pubmed/28404905
http://dx.doi.org/10.18632/oncotarget.15611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444721/
https://www.ncbi.nlm.nih.gov/pubmed/28404905
http://dx.doi.org/10.18632/oncotarget.15611

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