Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells

Diabetes is one of high risk factors for cardio- and cerebra-vascular diseases, including stroke, atherosclerosis and hypertension. This study was conducted to elucidate whether and how thromboxane receptor (TPr) activation contributes to blood-brain barrier (BBB) dysfunction in diabetes. Human brai...

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Detalles Bibliográficos
Autores principales: Zhao, Zhihong, Hu, Jue, Gao, Xiaoping, Liang, Hui, Yu, Haiya, Liu, Suosi, Liu, Zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444723/
https://www.ncbi.nlm.nih.gov/pubmed/28415790
http://dx.doi.org/10.18632/oncotarget.16273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444723/
https://www.ncbi.nlm.nih.gov/pubmed/28415790
http://dx.doi.org/10.18632/oncotarget.16273

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