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Hyperglycemia via activation of thromboxane A2 receptor impairs the integrity and function of blood-brain barrier in microvascular endothelial cells

Diabetes is one of high risk factors for cardio- and cerebra-vascular diseases, including stroke, atherosclerosis and hypertension. This study was conducted to elucidate whether and how thromboxane receptor (TPr) activation contributes to blood-brain barrier (BBB) dysfunction in diabetes. Human brai...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhihong, Hu, Jue, Gao, Xiaoping, Liang, Hui, Yu, Haiya, Liu, Suosi, Liu, Zhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444723/ https://www.ncbi.nlm.nih.gov/pubmed/28415790 http://dx.doi.org/10.18632/oncotarget.16273

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