Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells

Lysosomal acid lipase (LAL) is a critical neutral lipid metabolic enzyme that regulates metabolic reprogramming in myeloid-derived suppressor cells (MDSCs) through over-activation of mammalian target of rapamycin (mTOR). Affymetrix GeneChip microarray analysis of MDSCs from LAL deficient mouse (lal(...

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Detalles Bibliográficos
Autores principales: Ding, Xinchun, Zhang, Wenjing, Zhao, Ting, Yan, Cong, Du, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444731/
https://www.ncbi.nlm.nih.gov/pubmed/28415797
http://dx.doi.org/10.18632/oncotarget.16280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444731/
https://www.ncbi.nlm.nih.gov/pubmed/28415797
http://dx.doi.org/10.18632/oncotarget.16280

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