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Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells

Lysosomal acid lipase (LAL) is a critical neutral lipid metabolic enzyme that regulates metabolic reprogramming in myeloid-derived suppressor cells (MDSCs) through over-activation of mammalian target of rapamycin (mTOR). Affymetrix GeneChip microarray analysis of MDSCs from LAL deficient mouse (lal(...

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Detalles Bibliográficos
Autores principales:	Ding, Xinchun, Zhang, Wenjing, Zhao, Ting, Yan, Cong, Du, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444731/ https://www.ncbi.nlm.nih.gov/pubmed/28415797 http://dx.doi.org/10.18632/oncotarget.16280

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