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Interaction between granulin A and enolase 1 attenuates the migration and invasion of human hepatoma cells

Granulin A (GRN A), a peptide with a molecular 6 kDa, is derived from proteolysis of progranulin (PGRN). Previous study in our laboratory has shown that GRN A is able to inhibit cancer cell growth significantly. In the present study, we confirmed that GRN A can bind to α-enolase (ENO1) specifically...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoliang, Xu, Huanli, Wu, Ning, Liu, Xiujun, Qiao, Gan, Su, Shuonan, Tian, Ye, Yuan, Ru, Li, Cong, Liu, Xiaohui, Lin, Xiukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444744/
https://www.ncbi.nlm.nih.gov/pubmed/28415822
http://dx.doi.org/10.18632/oncotarget.16328