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Extracellular calcium promotes bone formation from bone marrow mesenchymal stem cells by amplifying the effects of BMP-2 on SMAD signalling

Understanding the molecular events that regulate osteoblast differentiation is essential for the development of effective approaches to bone regeneration. In this study, we analysed the osteoinductive properties of extracellular calcium in bone marrow-derived mesenchymal stem cell (BM-MSC) different...

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Detalles Bibliográficos
Autores principales: Aquino-Martínez, Rubén, Artigas, Natalia, Gámez, Beatriz, Rosa, José Luis, Ventura, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444778/
https://www.ncbi.nlm.nih.gov/pubmed/28542453
http://dx.doi.org/10.1371/journal.pone.0178158