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Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats

Successful drug therapies for treating ocular diseases require effective concentrations of neuroprotective compounds maintained over time at the site of action. The purpose of this work was to assess the efficacy of intravitreal controlled delivery of tauroursodeoxycholic acid (TUDCA) encapsulated i...

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Detalles Bibliográficos
Autores principales: Fernández-Sánchez, Laura, Bravo-Osuna, Irene, Lax, Pedro, Arranz-Romera, Alicia, Maneu, Victoria, Esteban-Pérez, Sergio, Pinilla, Isabel, Puebla-González, María del Mar, Herrero-Vanrell, Rocío, Cuenca, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444790/
https://www.ncbi.nlm.nih.gov/pubmed/28542454
http://dx.doi.org/10.1371/journal.pone.0177998