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Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats
Successful drug therapies for treating ocular diseases require effective concentrations of neuroprotective compounds maintained over time at the site of action. The purpose of this work was to assess the efficacy of intravitreal controlled delivery of tauroursodeoxycholic acid (TUDCA) encapsulated i...
Autores principales: | Fernández-Sánchez, Laura, Bravo-Osuna, Irene, Lax, Pedro, Arranz-Romera, Alicia, Maneu, Victoria, Esteban-Pérez, Sergio, Pinilla, Isabel, Puebla-González, María del Mar, Herrero-Vanrell, Rocío, Cuenca, Nicolás |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444790/ https://www.ncbi.nlm.nih.gov/pubmed/28542454 http://dx.doi.org/10.1371/journal.pone.0177998 |
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