Cargando…

A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling

The use of gene expression signatures to classify compounds, identify efficacy or toxicity, and differentiate close analogs relies on the sensitivity of the method to identify modulated genes. We used a novel ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq®, to dete...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeakley, Joanne M., Shepard, Peter J., Goyena, Diana E., VanSteenhouse, Harper C., McComb, Joel D., Seligmann, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444820/
https://www.ncbi.nlm.nih.gov/pubmed/28542535
http://dx.doi.org/10.1371/journal.pone.0178302