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Combination therapy of cancer with cancer vaccine and immune checkpoint inhibitors: A mathematical model
In this paper we consider a combination therapy of cancer. One drug is a vaccine which activates dendritic cells so that they induce more T cells to infiltrate the tumor. The other drug is a checkpoint inhibitor, which enables the T cells to remain active against the cancer cells. The two drugs are...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444846/ https://www.ncbi.nlm.nih.gov/pubmed/28542574 http://dx.doi.org/10.1371/journal.pone.0178479 |