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Structurally optimized analogs of the retrograde trafficking inhibitor Retro-2cycl limit Leishmania infections
In infected mammalian cells, Leishmania parasites reside within specialized compartments called parasitophorous vacuoles (LPVs). We have previously shown that Retro-2, a member of a novel class of small retrograde pathway inhibitors caused reduced LPV sizes and lower parasite numbers during experime...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444862/ https://www.ncbi.nlm.nih.gov/pubmed/28505157 http://dx.doi.org/10.1371/journal.pntd.0005556 |