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Antigen delivery to dendritic cells shapes human CD4(+) and CD8(+) T cell memory responses to Staphylococcus aureus

Intracellular persistence of Staphylococcus aureus favors bacterial spread and chronic infections. Here, we provide evidence for the existence of human CD4(+) and CD8(+) T cell memory against staphylococcal antigens. Notably, the latter could provide a missing link in our understanding of immune con...

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Detalles Bibliográficos
Autores principales: Uebele, Julia, Stein, Christoph, Nguyen, Minh-Thu, Schneider, Anja, Kleinert, Franziska, Tichá, Olga, Bierbaum, Gabriele, Götz, Friedrich, Bekeredjian-Ding, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444865/
https://www.ncbi.nlm.nih.gov/pubmed/28542586
http://dx.doi.org/10.1371/journal.ppat.1006387